F.A.Q. on Continued Availability of Compounded GLP-1 Medications

Updated: 3/20/2025

1. What is happening with compounded tirzepatide and semaglutide?

A recent court ruling and changes in FDA guidance may impact the availability of compounded GLP-1 medications, including tirzepatide and semaglutide. 

However, our 503A pharmacy partner has confirmed that they will continue filling prescriptions for compounded GLP-1s, as long as there is a clinically significant difference from the commercially available versions.

2. Is Reset Solutions still able to provide compounded tirzepatide and semaglutide?

Yes! There are no changes to availability at this time. Our 503A pharmacy partner will continue to compound GLP-1 medications under the following conditions:

• The medication is not commercially available (i.e. it is on the FDA's shortage list), OR
• A patient requires a clinically significant difference, such as:
  • An excipient-free formulation (for patients with allergies or sensitivities)
  • A specific concentration adjustment (for example, better dose titration)
  • An alternative delivery form necessary for a particular patient

Reset Solutions continues to work closely with our pharmacy partner to ensure ongoing access.

3. Should I refill my tirzepatide or semaglutide prescription now?

Yes. While there are no immediate changes, we recommend refilling your prescription as soon as possible to secure your current pricing and avoid potential future disruptions.

4. What happens if compounded GLP-1s become unavailable in the future?

If future regulatory changes restrict compounding further, Reset Solutions has a plan in place to ensure you still have access to GLP-1 medications:

• Lilly Direct: If compounded tirzepatide is no longer available, we can transition patients to Zepbound (brand-name tirzepatide) through Lilly Direct, with pricing starting at $399-$499 per month, depending on dosage.
• Other available options: We will work with each patient individually to determine the best alternative based on medical needs and budget.

5. Does this impact all providers or just Reset Solutions?

These regulations apply to all providers and compounding pharmacies nationwide. If restrictions are enforced, they will affect every clinic offering compounded GLP-1s—not just Reset Solutions.

6. How will Reset Solutions support me through these changes?

We are committed to keeping you informed and ensuring continued access to GLP-1 medications at the best available price. Reset Solutions will continue working with our pharmacy partners and evaluating all options to minimize any potential disruptions.